In bioresearch, applications dealing with study subjects on a microscopic scale, such as cell biology, have benefited from rapid development in automation in recent years.  Cutting-edge technology increases efficiency, accuracy, and productivity of laboratory workflow and can improve traceability in regulated environments.

Automated cell counters are an example of a product designed to streamline cell research. This blog post will review how automated cell counters are used for optimal sample preparation while conducting single-cell genomics research. This blog post will also highlight resources available while considering including automated cell counters in specialized research applications.

Ensuring High-Quality Cell Samples Using Automated Cell Counters

In the field of single-cell genomics, maintaining the quality of the cell samples being studied is paramount to being able to extract usable and accurate data from individual cells. KOTAI Biotechnologies is one such company that engages with genomics on a single-cell scale. A provider of innovative single-cell sequencing workflows, KOTAI Biotechnologies relies on innovative technology to assess the viability of cell samples for sequencing.

However, a practical challenge to studying individual cells and performing single nucleus sequencing lies in the sample quality. High-quality cell samples allow successful and efficient experiments to be conducted, and sometimes samples are littered with debris or dead cells that are unable to be sequenced and thus need to be removed.

To solve this challenge, KOTAI Biotechnologies utilized the DeNovix CellDrop™ FL Automated Cell Counter. Part of a line of automated cell counters by DeNovix, this instrument fully automates the cell counting process and provides more accurate results than manual counting procedures. Confirming the quality of cell samples before sequencing allows researchers to perform precise downstream analysis and follow-up experiments. In this key study, automated cell counters confirmed cells were in an acceptable and usable state to be sequenced and provided an accurate cell count, helping to standardize samples that different researchers prepared.

The application of automated cell counters in single-cell genomics has significant impacts on applications such as ATAC-Seq, ensuring high-quality nuclei preparations for library preparation and sequencing. Automated cell counters contribute to investigations into biological underpinnings of disease and the development of treatments through improved data quality and eliminating subjectivity in the cell counting process.

CellDrop™ Automated Cell Counters By DeNovix

As an expert in the area of RNA quantification and single-cell genomics, DeNovix is uniquely positioned to provide advanced biotechnology solutions to the scientific community. DeNovix instruments are a powerful solution for life sciences, as seen through the use of CellDrop™ Automated Cell Counters in various innovative biomedical studies.

This blog post provided a specific case study where automated cell counters optimized cell biology research by ensuring high-quality cell samples. As an industry leader in advanced instrumentation for life sciences research, DeNovix can provide solutions to your cell counting needs with our line of automated cell counters.

We offer different products for a variety of advanced procedures that facilitates the efficiency of cell counting. Our CellDrop™ Automated Cell Counters can count cells without slides, feature DirectPipette™ Technology, are accurate across a wide range of cell size and density, and prioritize user-friendliness. If you would like to learn more information about automated cell counters and their uses, please reach out to a member of our experienced team today.