DeNovix Instrumentation, Technology and Developments

03 Aug

Cell Counting: Measuring PBMCs in Whole Blood

Peripheral blood mononuclear cells (PMBCs) play a key part in keeping our bodies healthy. They derive from a process known as hematopoiesis, where hematopoietic stem cells (HTCs) in bone marrow generate highly-specialized immunological cells under lymphoid and myeloid lineages. These include dendritic cells (DCs), monocytes, and lymphocytes (B, NK, and T cells), which are responsible

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21 Jul

AO/PI Fluorescence Assays vs. Trypan Blue

Life scientists leverage a range of fluorescent dyes and assays when it comes to cell viability testing including trypan blue, acridine orange (AO), and propidium iodide (PI). Trypan blue is one of the most common reagents used in culture labs and biosciences to selectively stain dead tissues as part of cell viability testing. AO/PI fluorescence

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26 Jun

DS-11 Spectrophotometers: Best Practices

Spectrophotometry is a key technique in the analytical chemist’s arsenal, enabling quantitative measurements of the characteristic absorbance properties of different molecules. A measurement signal, typically in the ultraviolet-visible (UV-Vis) or infrared (IR) spectra, is used to probe sample materials and uncover various phenomenological optical properties. Spectrophotometers can uncover a wide range of key properties, including

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25 May

Cell Counting with Trypan Blue

Numerous procedures are available for biologists exploring overall cell count and cell viability, utilizing a choice of instrumentation and consumable assays. Hemocytometry is the traditional tool of manual cell counting and trypan blue is one of the most ubiquitous cell exclusion dyes used in medical and life science laboratories. However, the exclusion dye trypan blue

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12 May

NanoDrop™ Competitors for Microvolume Analysis

Absorbance spectroscopy and fluorescence methods are key tools when it comes to quantifying both deoxyribonucleic and ribonucleic acids (DNA and RNA). Traditionally, biochemists filled measurement capillaries and cuvettes with sample volumes on the scale of milliliters. Novel technologies for molecular analysis have significantly improved the quality of results attained from progressively smaller sample volumes, gradually

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hemocytometer
27 Apr

Common Challenges of Cell Counting with a Hemocytometer

Manual cell counting remains the standard method of measuring cell concentration and viability in many laboratories, but automated systems are rapidly eclipsing the capabilities of Hemocytometers. Initially derived as a method of acquiring a total count for blood cells in suspension, the applications of manual cell counting with Hemocytometers has expanded significantly since its inception

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10 Apr

DeNovix the Leading NanoDrop™ Alternative

At DeNovix Inc., we specialize in the development of convenient, high-precision instruments that meet the ever-changing demands of modern life sciences applications. We design, manufacture, and supply a sophisticated range of laboratory equipment based on years of hands-on experience with the best-in-class cell counters, fluorometers, and spectrophotometers. This has empowered us to deliver award-winning equipment

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celldrop_fl
10 Mar

Automated Cell Counters: Protocol Settings Explained

With a host of integrated application settings, CellDropTM automated cell counters provide innovative solutions for high-reliability analytical testing in biochemistry and life sciences facilities. These instruments automate cell counting processes and provide accurate viability assessments in seconds. With dual fluorescence and brightfield optics, they can streamline processes by accelerating initial counting and removing the margins

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28 Feb

Automated Cell Counter Principles

Automated cell counters offer a convenient solution to the challenges facing life science researchers today by providing precise results in a fraction of the time taken for manual cell counting. CellDrop™ systems from DeNovix build on the fundamental throughput benefits of established automated cell counting principles with a suite of additional usability advantages. By eliminating

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18 Dec

Best Practice for CellDrop Series Cell Counters

Cell counting can be a laborious process, with slow workflows and strict process control standards. These complications are compounded by elements of subjectivity when it comes to overall count and viability tests. Biologists running tests via hemocytometry or slide-based microscopy must individually carry out measurements, making judgment calls on cell identification or viability, which can

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